Job Posting: Vertex Pharmaceuticals

Requisition xxxx BR

Posting Title:  Scientist I, Analytical Development

Location:  Boston, MA

Department:  Analytical Development

Classification: R&D/Science

Occupation Name: Pharmaceutical Research

Required Travel: 10%

Required Education: PhD

Relocation: Yes

Vertex Pharmaceuticals Incorporated is a global biotechnology company committed to the discovery and development of breakthrough small molecule drugs for serious diseases. The Company’s strategy is to commercialize its products both independently and in collaboration with major pharmaceutical companies.

Position Overview:

Vertex is seeking a talented individual to join our Analytical Development group in Boston, MA.  As a member of the Analytical Development team, this role will support the drug development programs at Vertex through analytical method development, validation and transfer efforts, with special emphasis on drug substance support, drug product support or both. Expertise in laboratory techniques commonly used in the analysis of pharmaceutical products, especially HPLC, is required.

Key Responsibilities include but are not limited to:

- Develop methods to determine potency, purity, and stability for drug substances and/or drug products

- Set drug substance and drug product specifications with the understanding of clinical study design and CMC processes

- Justify and set retest period, storage, and shipping conditions

- Understand drug substance and drug product development to independently provide requisite analytical support

- Identify critical in-process-control issues and develop appropriate IPC methods

- Design stability studies for drug substance and drug product

- Design validation protocols that are appropriate for validating methods for their intended use.

- Present to cross functional teams and effectively communicate critical analytical issues and solutions

- Develop and review source documents for regulatory submissions

Basic Qualifications

- A Ph.D. degree in the life or physical sciences with a preference for a concentration in Chemistry, Analytical Chemistry or Pharmaceutical Chemistry

- Minimum Experience: 0 - 3 years current and relevant industry experience working in drug substance and drug product support

- Understanding of the drug development process, including chemical development and formulation development, is essential

- Good understanding of ICH and FDA method validation guidelines are essential.  The ability of to understand the guidelines in context of development phase is preferred.

- Good understanding of GMP and hands-on GMP experience as well as how to develop GMP friendly methods is preferred.

- Skilled in HPLC, GC, FT-IR, UV-VIS, KF, dissolution and other instruments is essential.  Strong expertise in HPLC is preferred.

- The ability to work successfully in both a team/matrix environment as well as independently is essential

- The ability to work in a fast pace environment, manage priorities, and maintain timelines for multiple projects is essential

- Excellent written and verbal communication skills as demonstrated by symposia presentations and research publications in peer reviewed journals are essential

Internship: Eastern Research Group

Job Posting:

Eastern Research Group, Inc. (ERG) is hiring paid interns to support an onsite project being conducted at the Agency for Toxic Substances and Disease Registry (ATSDR) in Atlanta. The work will involve data entry for an important environmental health investigation being conducted by ATSDR, and those we hire must have a keen eye for detail, familiarity with reviewing and interpreting environmental sampling data (preferably groundwater, air, and/or soil vapor), and strong working knowledge of Microsoft Excel. Database management skills are also very desirable.

Candidates must have a B.S., M.S., or Ph.D. in environmental engineering, chemical engineering, environmental public health, earth and atmospheric sciences, mechanical engineering, or related field. Positions are open to graduates and graduate students. We expect the work to start in the August-September time frame and to last until June 30, 2016. Ideally, candidates will be able to work full-time for the duration of the project, but other schedules will be considered (e.g., part-time during the school year). Compensation will be commensurate with experience, starting at $20/hour.

All work on this project will be conducted at the ATSDR campus, and thus, all hired employees must undergo a background check to obtain a security clearance prior to starting work. This is an excellent opportunity to see first-hand the scientific processes that ATSDR goes through when evaluating the public health implications of exposure to environmental contamination.

Employees for this project must be selected no later than July 29, so please forward your cover letter and resume as soon as possible to Will Morgan (William.Morgan@erg.com). Any inquiries about the project should also be sent via e-mail.

Job Posting: Intel Corporation

PTD Module & Integration Device Yield Engineer - 732752 

Description

PTD Module Engineers are responsible for leading scientific research and enabling manufacture of innovative device architectures coupled with the realization of these architectures. Responsibilities include designing, executing and analyzing experiments necessary to meet engineering specifications for their process. A Module Engineer participates in the development of intellectual property and the development of the equipment necessary to exploit understanding gained in research (in collaboration with equipment suppliers.) The Engineer must work effectively with the equipment supplier to identify shortcomings, propose and evaluate hardware modification to mitigate issues and operate the manufacturing line in order to integrate the many individual steps necessary for the manufacture of complex microprocessors. Module Engineers are also responsible for overseeing in-situ ramp to manufacturing volumes to demonstrate that the technology meets requirements while simultaneously transferring the technology to counterparts in manufacturing via 'Copy Exactly!' methodology. Module ownership includes the install and qualification of manufacturing capacity at the development site and audit installation/qualification and supervision of first full loop at the production site. Must hold a PhD. 

Qualifications

You must possess a minimum of a Ph.D. degree majoring in Physics, Material Science, Chemical Engineering, Electrical Engineering, Mechanical Engineering, or Chemistry.

PhD candidates should meet the additional following criteria:

- Demonstrated experience in keen experimental insight and ability to devise and focus on key experiments

- Excellent written and verbal communication skills

- Highly motivated and excited by self-directed hands-on work

- Creative and flexible to thrive under changing priorities

- Teamwork skills

- Familiarity or expertise with semiconductor processing is a plus but not necessary

- Minimum GPA = 3.5/4.0 for undergraduate and graduate education

Job Category

Engineering 

Primary Location

USA-Oregon, Hillsboro 

Full/Part Time

Full Time

Posting Date

Dec 5, 2014 

Apply Before

Dec 5, 2015 

Business Group

 As the world's largest chip manufacturer, Intel strives to make every facet of semiconductor manufacturing state-of-the-art -- from semiconductor process development and manufacturing, through yield improvement to final test and optimization, and lastly packaging. Employees in the Technology and Manufacturing group are part of a worldwide network of manufacturing and assembly/test facilities. 

Posting Statement

Intel prohibits discrimination based on race, color, religion, gender, national origin, age, disability, veteran status, marital status, pregnancy, gender expression or identity, sexual orientation or any other legally protected status.